There were 468 homicides in Chicago last year, an increase from 416 murders in 2014, according to new police department data.
A review by the Chicago Tribune shows that no other U.S. city had as many homicides as Chicago last year.
The number of shooting victims in Chicago also ticked up from 2,600 in 2014 to 2,939 in 2015.
Meanwhile, the city logged 22 officer-involved shootings in 2015, down from 37 in 2014, according to the Chicago Tribune.
Since 2011, overall crime in the city has decreased by 37 percent, according to the police department, which is facing intense public scrutiny over the Laquan McDonald case and other high-profile fatal police shootings. In light of the controversy, the U.S. Justice Department launched a broad investigation into the Chicago Police Department's practices last month.
The Chicago Police Department is also implementing a series of reforms, including the expansion of police Tasers and body cameras.